*Note: All data is from the 1985 tournament to the present.

Know your seed
No. 1 No. 9
No. 2 No. 10
No. 3 No. 11
No. 4 No. 12
No. 5 No. 13
No. 6 No. 14
No. 7 No. 15
No. 8 No. 16
The 1997 4-seed Arizona Wildcats became the first team in the 64-team format to defeat three No. 1 seeds en route to the national championship. As tough it was to defeat Kansas, North Carolina and Kentucky, the Wildcats’ first game of the tournament was no walk in the park, thanks to No. 13 seed South Alabama. Arizona had to overcome a 10-point deficit before it eventually closed on a 22-4 run to beat South Alabama, 65-57 and start its championship run.

The number of highly contested games between the No. 4 and No. 13 seeds have grown. Although the top seed has a .797 winning percentage, the average margin has only been 9.4 points in favor of the fourth-seeded teams. Additionally in the past 17 years, all four-seeds have moved out of the first round just five times.

Last year was a slow one for the No. 4-seed. California lost to No. 13 Hawaii in the opening round, Kentucky was knocked out by No. 5 Indiana in the Round of 32, and while Duke and Iowa State made it to the Sweet 16, both lost by double digits there.

Louisville owns the most appearances as a No. 4 seed. The Cardinals maintain an 8-1 first-round record, with the lone loss in a 2011 thriller to Murray State. Two of Louisville's wins were by 19 points and 22 points but the rest were decided by single-digits including a two-point win over UC Irvine in 2015.