LOUISVILLE, Ky. — Monique Reid scored 28 points and Louisville’s defense shut down No. 7 DePaul in a 68-55 win on Wednesday.
Shoni Schimmel added 11 points, eight rebounds and six assists for the Cardinals (18-10, 9-5 Big East), who knocked off a ranked team at home for the fifth time this season.
Keisha Hampton led the Blue Demons (25-4, 12-2) with 20 points but DePaul shot just 34 percent from the field and turned it over 20 times while posting its lowest point total of the season.
The Cardinals led by as much as 15 in the second half. DePaul pulled within seven points on two different occasions.
DePaul’s best chance came when it closed to within 57-50 with just over 4 minutes to go but the Blue Demons came up empty on three possessions in a row and the Cardinals were able to collect themselves and pull away.