Houston senior quarterback Case Keenum established the FBS record with his 139th career touchdown pass as the 18th-ranked Cougars routed Rice 73-34 on Thursday night.

Here are the FBS players with at least 100 career touchdown passes:

Case Keenum was the C-USA Preseason Offensive Player of the Year in 2009, '10 and '11.
AP Images
KEENUM'S NINE TD PASSES
Qtr. Receiver Yards
1 Patrick Edwards 57
2 Myron Carrier 21
2 Patrick Edwards 64
2 Justin Johnson 18
3 Charles Sims 41
3 Charles Sims 20
3 Patrick Edwards 37
3 Patrick Edwards 22
4 Patrick Edwards 47

Case Keenum began his college career at Houston in 2006, when he was redshirted. In 2008, he led the nation in total offense as the Cougars won their first bowl game since 1980. He was injured during the 2010 season and was granted a sixth year of eligibility for '11. He became the FBS career leader in total offense on Oct. 22, eclipsing the previous record (16,910 yards) set by Hawaii's Timmy Chang.

On Thursday night in an often-driving rain, Keenum threw nine TD passes -- five in the second half -- to set the mark for career TD passes with 139. He eclipsed Graham Harrell's record on a 41-yard scoring pass -- Keenum's fifth of the game -- to Charles Sims with 11:35 remaining in the third quarter.

Keenum finished the game 24 of 37 for 534 yards. He also threw one interception. Patrick Edwards had seven catches for 318 yards and five touchdowns.

 

Graham Harrell won the Johnny Unitas Golden Arm Award in 2008.
AP Images

Graham Harrell finished his Texas Tech career with an NCAA-record 134 passing touchdowns, breaking the previous mark of 131 set by Colt Brennan. In 2008, Harrell compiled 5,111 passing yards, becoming the first player to post multiple 5,000-yard passing seasons (2007 and '08).

Colt Brennan was awarded the Sammy Baugh Trophy in 2006.
AP Images

Colt Brennan set the record for touchdown passes on Nov. 23, 2007, throwing five against Boise State to surpass the mark set by BYU's Ty Detmer. Among the records held by Hawaii's Brennan: single-season record for most TD passes (58 in 2006), season passing efficiency (186.0 in '06), and the career mark for highest pass completion percentage (70.4).

Kellen Moore was tabbed the WAC Offensive Player of the Year in 2009 and '10.
AP Images

Kellen Moore was named a finalist for the Heisman Trophy in 2010, the first Boise State player to be a finalist for the award. With the Broncos' victory against Air Force on Oct. 22, he tied former Texas QB Colt McCoy with 45 wins. After a bye week, Moore can take sole possession of the record on Nov. 5 at UNLV.

In 1990, Ty Detmer won the Heisman Trophy, Davey O'Brien Award and Maxwell Award.
Getty Images

Ty Detmer finished his BYU tenure with 1,530 pass attempts; 958 completions; 15,031 passing yards; 121 touchdown passes; 14,665 yards of total offense; 135 total touchdowns; and 162.7 passer rating -- all were NCAA records at the time. He held 59 NCAA records and tied for three others.

Timmy Chang was named 2003 Hawaii Bowl MPV and co-MVP of the 2004 Hawaii Bowl.
AP Images

Timmy Chang played five seasons (2000-04) for Hawaii, where he started 50 of 53 games. He completed 1,388 of 2,436 passes (57 percent) for 17,072 yards and 117 TDs, breaking records of 1,231 completions in 1,883 attempts by Texas Tech's Kliff Kingsbury and 15,031 yards by BYU's Ty Detmer. Chang's 16,910 yards in total offense also eclipsed Detmer's previous record (14,465).

Tim Rattay finished in the top 10 in voting for the Heisman in 1998.
Getty Images

Tim Rattay still holds several records, including average passing yards per game (386.2) and is second with 12,643 yards of total offense. He ended his career in the top five of every offensive category. Rattay set Louisiana Tech  school records as a senior with 4,943 yards and 46 TDs to finish second in NCAA history in yardage.

During his Heisman-winning season of 1996, Danny Wuerffel was 207 of 360 for 3,625 yards and 39 TDs.
AP Images

Danny Wuerffel finished his career by completing 708 of 1,170 passes for 10,875 yards with 114 TD passes, the best in SEC history and second-most in FBS annals. His career pass efficiency rating (163.56) was the all-time mark and his percentage of passes which went for a TD (9.74) ranked first. In 1995, his efficiency rating (178.4) set the single-season record. In '96, his efficiency rating (170.6) made him the first to post a rating of 170 or better in consecutive years.

In 2009, Colt McCoy won the Johnny Unitas Golden Arm, Davey O'Brien Maxwell and Walter Camp awards.
AP Images

Colt McCoy, the 2008 Walter Camp Award winner, won more games as an FBS quarterback (45) than anyone else in history. In 2009, he won 13 of the top 15 major college player awards, including offensive player of the year. McCoy is one of the two FBS quarterbacks to average 10 wins per season for four seasons (Andy Dalton; Kellen Moore is on pace to become the third.)

As a redshirt freshman, Dan LeFevour led CMU to victory in the 2006 Motor City Bowl.
AP Images

Dan LeFevour was the second player in FBS history to pass for more than 3,000 yards and rush for 1,000-plus yards in a single season (Vince Young). On Sept. 12, 2009, LeFevour passed Byron Leftwich as the MAC all-time leader in total offense. LeFevour is the only player in NCAA history with more than 12,000 passing yards and 2,500 rushing yards. He also holds the FBS record for total touchdowns (150).

Chase Daniel was a 2007 finalist for the Maxwell, Manning, Walter Camp and Davey O'Brien awards.
AP Images

Chase Daniel was a three-year starter at Mizzou and was a Heisman Trophy candidate in 2007 and '08. He finished his career with a school-record 13,256 yards in total offense, erasing Brad Smith's previous mark of 13,088. Daniel finished fourth in the Heisman voting in 2007 and was a second team All-America selection in '08.

Chad Pennington earned MVP honors as Marshall won its first bowl game, 48-29 against Louisville in the 1998 Motor City Bowl.
Getty Images

Chad Pennington was to be redshirted his freshman season (1995), however he led Marshall to the Division I-AA Championship Game. The following year, Pennington was redshirted. He returned to play in 1997 as Marshall moved to Division I-A. In 1999, Pennington led Marshall to a 13-0 record and finished his career 1,026 of 1,619 for 13,423 yards and 115 TDs with only 45 interceptions.

FBS: MOST CAREER TOUCHDOWN PASSES
Rank Player School (Seasons) No.
Bold denotes active. Statistics through Oct. 27, 2011.
1 Case Keenum Houston (2007-11) 139
2 Graham Harrell Texas Tech (2005-08) 134
3 Colt Brennan Hawaii (2004-07) 131
4 Kellen Moore Boise State (2008-11) 123
5 Ty Detmer BYU (1988-91) 121
6 Timmy Chang Hawaii (2000-04) 117
7 Tim Rattay Louisiana Tech (1997-99) 115
8 Danny Wuerffel Florida (1993-96) 114
9 Colt McCoy Texas (2006-09) 112
10 Dan LeFevour Central Michigan (2006-09) 102
11 Chase Daniel Missouri (2005-08) 101
12 Chad Pennington Marshall (1995, 1997-99) 100
13 Chase Clement Rice (2005-08) 99
  Tim Hiller Western Michigan (2005, '07-09) 99
  Matt Leinart USC (2002-05) 99
16 Trevor Vittatoe UTEP (2007-10) 97
17 Kliff Kingsbury Texas Tech (1999-2002) 95
  Brady Quinn Notre Dame (2003-06) 95
  Philip Rivers NC State (2000-03) 95
20 Max Hall BYU (2007-09) 94
21 Russell Wilson NC State (2008-10), Wisconsin (2011) 92
22 David Klingler Houston (1988-91) 91
23 Todd Reesing Kansas (2006-09) 90
24 Byron Leftwich Marshall (1998-2002) 89
  Peyton Manning Tennessee (1994-97) 89
26 Sam Bradford Oklahoma (2007-09) 88
  Chris Leak Florida (2003-06) 88
  Jordan Palmer UTEP (2003-06) 88
  Tim Tebow Florida (2006-09) 88
30 Chad Henne Michigan (2004-07) 87
  Troy Kopp Pacific (1989-92) 87
  Tim Lester Western Michigan (1996-99) 87
  Luke McCown Louisiana Tech (2000-03) 87
34 Ken Dorsey Miami (Fla.) (1992-95) 86
35 Bruce Gradkowski Toledo (2002-05) 85
  Chase Holbrook New Mexico State (2005-08) 85
  Landry Jones Oklahoma (2009-11) 85
  Kevin Kolb Houston (2003-06) 85
  Andrew Walter Arizona State (2001-05) 85