WEST LAFAYETTE, Ind. -- Natalie Novosel scored 17 points and Devereaux Peters added 16 points and 11 rebounds to help No. 3 Notre Dame defeat No. 12 Purdue 66-38 on Saturday.

Skylar Diggins added nine points, seven assists and six rebounds for the Fighting Irish

Notre Dame (9-1) has won six in a row since losing at No. 1 Baylor 94-81 on Nov. 20.

Saturday's Top-25 Results
No. 13 Ohio State 84, Canisius 41
No. 15 Louisville 92 , Gardner-Webb 27
Complete Scoreboard

Courtney Moses scored 14 points and Antionette Howard added 13 for Purdue (7-2), which was coming off a 60-51 win over No. 4 Texas A&M, the defending national champion, on Sunday. Purdue's Brittany Rayburn, Purdue's leading scorer for the season, was held to four points on 1-for-7 shooting. She was ill and played just 24 minutes.

Purdue produced one of its lowest offensive performances in school history. The Boilermakers shot just 24 percent from the field.

Notre Dame shot 44 percent against Purdue, which had been holding opponents to 31 percent shooting.

Notre Dame went on an early 17-0 run to take a 25-5 lead, and it could have been even larger had the Fighting Irish not missed several layups on passes by Diggins. Purdue went scoreless for more than seven minutes and missed 13 of its first 15 shots.

Notre Dame led 36-17 at halftime. Purdue shot 28 percent, committed 11 turnovers and was outrebounded 29-13 in the first 20 minutes. Peters had 10 points and eight rebounds before the break and Diggins had seven points, five assists and four rebounds. Rayburn, Purdue's leading scorer, went without a point in the first half.

The Fighting Irish extended their lead in the second half. Notre Dame led 58-30 with 10 minutes to play. Novosel scored 11 points in the first 10 minutes of the second half to help put the game out of reach. A breakaway layup by Diggins pushed the lead to 30 points.