Janie Harris | NCAA.com | September 30, 2016 10 numbers to know for the Louisville-Clemson game Louisville's Lamar Jackson looks to be a key player in the Louisville-Clemson game. Share For the second time this season, No. 3 Louisville prepares to face a top-five opponent. The Cardinals travel to Clemson's Death Valley to take on the No. 5 Tigers in what is the most anticipated game of Week 5. Saturday's showdown will be the third time the two teams meet. And, with star quarterbacks Deshaun Waston and Lamar Jackson leading their respective undefeated teams, this looks to be an exciting watch. But, before whipping your remote out to tune into this monster matchup, take a look at some numbers likely to impact the outcome of the game: 2021 ACC softball preview: Florida State leads deep conference Here's our 2021 ACC softball preview, including why Florida State is the favorite to win the conference title. READ MORE 2021 ACC baseball preview: Led by Louisville, the conference is deeper than ever The ACC has never been more loaded with legitimate postseason contenders. In fact, all 14 teams in the conference appear to have regional-caliber rosters — in any other year. READ MORE 2021 ACC football schedule: Games, dates, matchups This is a team-by-team schedule for the 2021 ACC college football season. READ MORE