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Andrew Cyr | NCAA.com | October 6, 2017

WATCH: Pratt secures NC State's upset vs. Louisville with pick six

With the ball in the reigning Heisman Trophy winner's hands in a one-score game with less than three minutes left in regulation, North Carolina State's defense needed to make a play to hold onto a potential in-conference upset. 

Enter Germaine Pratt.

RELATED: Jaylen Samuels breaks open 79-yard catch-and-run to set up NC State score

With Louisville on its own 11-yard line on second and 10, Pratt intercepted a tipped Lamar Jackson pass and returned it 25 yards for a pick six to secure a 39-25 upset win against the No. 17 Cardinals. 

Watch the full play here:

The win improves NC State to 5-1 (3-0 ACC)  while Louisville falls to 4-2 (1-2 ACC) and now finds itself two games back in the loss column to the Wolfpack and Clemson in the ACC Atlantic division.