SYRACUSE, N.Y. -- Jenna Caira threw her fourth career no-hitter as Syracuse (40-13, 17-5) defeated No. 16 South Florida (45-10, 17-5) 7-0 on Sunday afternoon on Senior Day at the SU Softball Complex.

In her last career start at home, Caira struck out eight Bulls and registered her 25th victory of the season. It was her second no-hitter of the campaign and she is now 25-6 with a 1.53 ERA on the year.

Carey-Leigh Thomas hit a grand-slam in the bottom of the first inning and Shirley Daniels smacked a two-run shot in the second to help Syracuse surge ahead. Daniels had a monster weekend at the plate, going 6-for-11 with two home runs, three RBIs and two runs scored.

Daniels led off the game with a single, then back-to-back walks by Veronica Grant and Stephanie Watts loaded the bases with no outs. After USF got the next two batters, Thomas hit an opposite-field shot off relief pitcher Sam Greiner for a 4-0 lead in the bottom of the first.

The Orange, who lead the Big East in home runs, added to their cushion in the bottom of the second inning when Daniels hit her fourth homer of the season. Her round-tripper came with one out and also scored Morgan Nandin who led off the inning with a single.

USF’s only base runner came in the fifth inning as Kourtney Salvarola reached via an error, but she would not advance past first base as Caira got Jessica Mouse to fly out which ended the inning.

SU maintained its 6-0 advantage until the fifth inning when Lacey Kohl’s sac fly scored Grant from third base. It was Kohl’s 100th career RBI, which ranks her fifth all-time at Syracuse.

With two outs in the seventh, Kenshyra Jackson ended the game on a groundout to third base as the Orange mobbed Caira at the mound to celebrate the no-hitter.

Syracuse reached the 40-win plateau for the second time in program history and for the second-consecutive season. Its conference record of 17-5 gives Syracuse the No. 3 seed in the upcoming Big East tournament as the Orange will look to capture their third consecutive tournament title.