Carson-Newman jumped into the power rankings after laying claim to their tenth tournament title.
In the Week 5 DII softball power rankings, Carson-Newman and West Florida entered the rankings.
Note: These power rankings are not affiliated with the NCAA selection committee and teams are ranked at the sole discretion of the writer.
| Rank | School | Record | Comments | Previous |
|---|---|---|---|---|
| 1 |
Angelo State |
51-4 | It heads into the Lone Star Conference Tournament on a 16-game winning streak. | 1 |
| 2 |
North Georgia |
44-10 | It heads into the Southeast Regional, May 11-13, on a nine-game winning streak. | 2 |
| 3 |
Minnesota State |
50-6 | It reached 50 wins for first time since 2011. | 4 |
| 4 |
Harding |
50-6 | It became just the second team in GAC history to reach 50 wins. | 5 |
| 5 |
West Texas A&M |
40-9 | It outscored opponents 36-6 during a four-game winning streak. | 6 |
| 6 |
West Virginia Wesleyan |
40-6 | It heads into the MEC Tournament on a 15-game winning streak. | 7 |
| 7 |
Central Oklahoma |
47-9 | It won the MIAA regular-season and tournament titles. | 10 |
| 8 |
Colorado Mesa |
42-6 | It prepares for RMAC Tournament with a perfect 20-0 home record. | 9 |
| 9 |
Pfeiffer |
44-6 | It lost in the championship game of the Conference Carolinas Tournament. | 3 |
| 10 |
Cal State Monterey Bay |
42-9 | It beat Humboldt State in its final regular-season game. | 8 |
| 11 |
Southern Indiana |
40-10 | The last four regular-season games were rained out. | 12 |
| 12 |
St. Mary’s (TX) |
40-12 | This is its fifth straight season with 40 or more wins. | 16 |
| 13 |
Humboldt State |
34-12 | It's preparing for the CCAA Tournament after splitting the regular season title with Monterey Bay. | 13 |
| 14 |
Carson-Newman |
43-11 | It won its tenth South Atlantic Conference Tournament. | NR |
| 15 |
California Baptist |
36-11 | It is in the middle of two and a half weeks without games before regionals start. | 15 |
| 16 |
West Florida |
39-12 | It allowed only one run in last three games. | NR |
